Industries

Helping clients meet their business challenges begins with an in-depth understanding of the industries in which they work. That’s why KPMG LLP established its industry-driven structure. In fact, KPMG LLP was the first of the Big Four firms to organize itself along the same industry lines as clients.

How We Work

We bring together passionate problem-solvers, innovative technologies, and full-service capabilities to create opportunity with every insight.

Learn more

Careers & Culture

What is culture? Culture is how we do things around here. It is the combination of a predominant mindset, actions (both big and small) that we all commit to every day, and the underlying processes, programs and systems supporting how work gets done.

Learn more

“One-and-done” gene therapies

A near-term niche?

The last decade has brought forth a revolution in the pharmaceutical industry with the launch of the first “one-and-done,” or potentially curative, gene therapies. From the launch of Luxturna for an inherited eye disease, to the entry of Zolgensma for spinal muscular atrophy (SMA), we are now in an era of innovation in which certain diseases can potentially be cured. However, for the time being we believe the focus will likely remain on rare and ultra-rare monogenic diseases until the field evolves and the major challenges of therapeutic delivery and manufacturing are addressed.

If this is the hand that biopharma companies have been dealt, how should they play it? What does this mean for short- and long-term business models? Should biopharma companies be spending big now in the hope that, in the long term, these therapies and their associated platforms will drive sustainable top- and bottom-line growth from more complex, larger-population diseases? In short, how can companies gain a competitive advantage in what will likely be a near-term niche while also developing a long-term presence in this innovative field?

YouTube thumbnail image

Gene therapy video series

"Join me as I interview a number of key stakeholders including patients groups, supply chain experts and those involved in the development, manufacturing and launch of these innovative technologies as they provide their
point of view on the promise and challenges related to gene therapy." - Alasdair Milton, PhD.

Dive into our thinking:

“One-and-done” gene therapies

Download PDF

Explore more

Thank you!

Thank you for contacting KPMG. We will respond to you as soon as possible.

Contact KPMG

Use this form to submit general inquiries to KPMG. We will respond to you as soon as possible.

By submitting, you agree that KPMG LLP may process any personal information you provide pursuant to KPMG LLP's Privacy Statement.

An error occurred. Please contact customer support.

Job seekers

Visit our careers section or search our jobs database.

Submit RFP

Use the RFP submission form to detail the services KPMG can help assist you with.

Office locations

International hotline

You can confidentially report concerns to the KPMG International hotline

Press contacts

Do you need to speak with our Press Office? Here's how to get in touch.

Headline